Figure 4
Comparison between adult and 10-day-old rat liver mitochondria for (A) GCDC-induced ROS generation, (B) GSH levels, GSH-Px and GSSG-R activities, and, (C) expression of Bcl-2 proteins. In panel A, young (solid symbol) and adult (open symbol) rat mitochondria were exposed to 0 μM (circle), 50 μM (triangle), 100 μM GCDC (square), or 100 μM GCDC + 5 μM CsA (diamond). *p < 0.05 between adult and 10-day-old rat hepatic mitochondria; **p < 0.005 between adult and 10-days old hepatic mitochondria using a student t test. Results were from at least four separate experiments.
