Abstract
Object of study: Headache and migraine is a common problem nowadays for an increasing number of children and adolescents At the last few years, there are some references in the literature about the correlation in adults between headache and Helicobacter Pylori infection The aim of the study was the investigation of the correlation between headache and Helicobacter Pylori infection in children.
Method: A total number of 65 children and adolescents aged 7,5 to 17 years were enrolled. All of them suffered from headache or migraine (international criteria 2001) and they were tested firstly using urea breath test(UBT) From the children and adolescents tested with UBT, 17 of them were found positive for Helicobacter Pylori infection These 17 children and adolescents were investigated with an upper GI endoscopy and received the proper therapy based on Helicobacter Pylori infected tissue culture and antibiogram.
Results: After 4 months of observation, starting 1 month after the end of the anti-helicobacter infection therapy, all 17 children and adolescents were free of headache and migraine symptoms.
Conclusion: Although these are preliminary findings, we can assume that Helicobacter Pylori infection maybe plays a role in the pathogenesis and phenotype expression of headache and migraine in children and adolescents.
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Karkelis, S., Papadaki-Papandreou, O., Lykogeorgou, M. et al. 667 Helicobacter Pylori Infection and Headache in Children and Adolescents. Pediatr Res 68 (Suppl 1), 340 (2010). https://doi.org/10.1203/00006450-201011001-00667
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DOI: https://doi.org/10.1203/00006450-201011001-00667
