Figure 3

Effects of Keto and/or Caff on retinal and choroidal HIF1α and 8-isoPGF2α. The upper panel (a–d) are data at P14 (IH), and the lower panel (e–h) are data at P21 (IHR). The white bars represent the room air (RA) controls and the black bars represent the intermittent hypoxia (IH) at P14 or recovery from IH (IHR) at P21. Retinal HIF1α are panels a and e; choroidal HIF1α are panels c and g; retinal 8-isoPGF2α are panels b and f; and choroidal 8-isoPGF2α are panels d and h at P14 (upper panel) and P21 (lower panel). Groups are as described in Figure 1. Data are presented as mean ± SEM (n = 6 samples/group). *P < 0.01; **P < 0.01 vs. Sal/Sal RA; ‡P < 0.01 vs. Sal/Sal IH; §P < 0.01 vs. RA.