Congratulations to Zachary A. Vesoulis, MD, this issue's Early Career Investigator! Read his Commentary to understand his passion for the autoregulation of cerebral blood flow. Comparing fractional tissue oxygen extraction between two groups of preterm infants (23–25 weeks and 26–28 weeks), he and his colleagues found that the less mature infants could not compensate for low blood pressure with an increase in the oxygen extraction. See pages 893 and 944

Alcohol use in high school students has been described, but little is known about drinking among middle school students. Zucco et al. describe widespread alcohol consumption among 12- to 15-year-olds in a province in Italy, and factors that increase the risk of drinking. See page 915

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