Table 1 SARS-CoV-2-derived candidate peptides bind MHC class I (HLA-A*24:02, HLA-A*02:01, or HLA-A*02:06)
ID | Protein | Sequence | Length (amino acids) | Starting position | Affinity (nM) | HLA | Conserved in |
|---|---|---|---|---|---|---|---|
P01 | ORF1ab | TYASALWEI | 9 | 4090 | 18 | A*24:02 | SARS-CoV |
P02 | S | PFAMQMAYRF | 10 | 897 | 39 | A*24:02 | SARS-CoV |
P03 | ORF1ab | YDYLVSTQEF | 10 | 3811 | 41 | A*24:02 | SARS-CoV |
P04 | ORF1ab | YYSQLMCQPI | 10 | 2560 | 44 | A*24:02 | SARS-CoV |
P05 | ORF1ab | SYYSLLMPI | 9 | 4628 | 46 | A*24:02 | SARS-CoV |
P06 | ORF1ab | AYANSVFNI | 9 | 5080 | 56 | A*24:02 | SARS-CoV MERS-CoV |
P07 | ORF1ab | RYKLEGYAF | 9 | 6676 | 62 | A*24:02 | SARS-CoV |
P08 | ORF1ab | FTYASALWEI | 10 | 4089 | 69 21 5 | A*24:02 A*02:01 A*02:06 | SARS-CoV |
P09 | ORF1ab | SYSLFDMSKF | 10 | 7039 | 85 | A*24:02 | SARS-CoV |
P10 | ORF1ab | RYFKYWDQTY | 10 | 4677 | 90 | A*24:02 | SARS-CoV |
P11 | ORF1ab | TAYANSVFNI | 10 | 5079 | 102 | A*24:02 | SARS-CoV MERS-CoV |
P12 | M | LWLLWPVTL | 9 | 54 | 108 | A*24:02 | SARS-CoV |
P13 | ORF1ab | TYASALWEIQ | 10 | 4090 | 111 | A*24:02 | SARS-CoV |
P14 | ORF1ab | YAYLRKHFSM | 10 | 5138 | 115 | A*24:02 | SARS-CoV |
P15 | ORF1ab | SLFDMSKFPL | 10 | 7041 | 6 18 | A*02:01 A*02:06 | SARS-CoV |
P16 | ORF1ab | LMYKGLPWNV | 10 | 6077 | 7 8 | A*02:01 A*02:06 | SARS-CoV |
P17 | ORF1ab | FVLWAHGFEL | 10 | 6108 | 8 13 | A*02:01 A*02:06 | SARS-CoV |
P18 | ORF1ab | YMPASWVMRI | 10 | 3654 | 12 103 | A*02:01 A*02:06 | SARS-CoV |
P19 | ORF1ab | MMGFKMNYQV | 10 | 5982 | 18 77 | A*02:01 A*02:06 | SARS-CoV |
P20 | ORF1ab | FELTSMKYFV | 10 | 6115 | 18 59 | A*02:01 A*02:06 | SARS-CoV |
P21 | ORF1ab | MMILSDDAV | 9 | 5147 | 35 13 | A*02:01 A*02:06 | SARS-CoV |
P22 | N | FGMSRIGMEV | 10 | 315 | 37 105 | A*02:01 A*02:06 | SARS-CoV |
P23 | ORF1ab | TLMIERFVSL | 10 | 5245 | 42 48 | A*02:01 A*02:06 | SARS-CoV |
P24 | ORF1ab | YVYNPFMIDV | 10 | 6160 | 51 15 | A*02:01 A*02:06 | SARS-CoV |
P25 | ORF1ab | NVLAWLYAAV | 10 | 3466 | 72 11 | A*02:01 A*02:06 | SARS-CoV |
P26 | ORF1ab | TLEPEYFNSV | 10 | 5740 | 79 22 | A*02:01 A*02:06 | SARS-CoV |
P27 | ORF1ab | YSFLPGVYSV | 10 | 3098 | 81 23 | A*02:01 A*02:06 | SARS-CoV |
P28 | ORF1ab | FMIDVQQWGF | 10 | 6165 | 84 29 | A*02:01 A*02:06 | SARS-CoV |
