Fig. 1: Identification of somatic variation in DGCs. | Experimental & Molecular Medicine

Fig. 1: Identification of somatic variation in DGCs.

From: Identification of genomic aberrations associated with lymph node metastasis in diffuse-type gastric cancer

Fig. 1

a Workflow for identifying somatic variants in 23 DGCs. Somatic mutations and indels were identified using Mutect and Varscan software, respectively. Mutated allele frequencies (MAF) are indicated. b Bar plots show the frequency of the recurrent variations in the DGC data (n = 23, top) and the DGC (n = 84) and IGC (n = 191) data from TCGA (bottom). The significance of the mutation frequency of DGC compared to that of other types is indicated (**P < 0.00001, *P < 0.05)

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