Fig. 1: Surgical procedure for the Masquelet’s induced membrane model in both the subcutaneous site and femoral defect site.
From: Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelet’s induced membrane in rats
a A 5-mm incision was created on the left thigh to create a 10-mm pocket. b The PMMA cylinder was inserted into the pocket. c The induced membrane formed in the subcutaneous region was exposed at 6 weeks after surgery. d A 10-mm critical-size femoral defect was created in the right femur, which has been previously fixed with a 6-well titanium mini-plate. e The PMMA spacer was inserted into the femoral defect area. f The induced membrane formed in the femoral defect site was exposed after 6 weeks of surgery
