Fig. 7: Inhibition of Notch1 promotes proliferation, migration and recruitment of EPCs.
From: Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelet’s induced membrane in rats
a–b The protein expression and quantitative data for Notch1, PCNA, ICAM-1 and SDF-1 in EPCs treated with control-siRNA or Notch1-siRNA. c–d The protein expression and quantitative data for Notch1, PCNA, ICAM-1 and SDF-1 in EPCs treated with the protein extracted from the induced membrane derived from the subcutaneous site and femoral defect site with or without DAPT intervention. The data in the figures represent averages ± S.D. Significant differences between the different groups are indicated as *P < 0.05, **P < 0.01; for each group, n = 5
