Fig. 2: The expression profile of miR-125a-5p in the pulmonary artery (PA) of MCT-PAH rats and in rat PASMCs. | Experimental & Molecular Medicine

Fig. 2: The expression profile of miR-125a-5p in the pulmonary artery (PA) of MCT-PAH rats and in rat PASMCs.

From: MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways

Fig. 2

a Compared to control rats (n = 6), miR-125a-5p was significantly downregulated in the PA of MCT-PAH rats at week 1 (n = 6), week 2 (n = 8), and week 3 (n = 8). b miR-125a-5p was significantly downregulated in MCT-PASMCs compared with control PASMCs. The expression level of miR-125a-5p was normalized to U6. **p < 0.01, ***p < 0.001, and ****p < 0.0001 vs. control; ##p < 0.01

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