Fig. 2: Inhibition of Kv1.5 currents by MK801 enantiomers recorded from CHO cells overexpressing Kv1.5. | Experimental & Molecular Medicine

Fig. 2: Inhibition of Kv1.5 currents by MK801 enantiomers recorded from CHO cells overexpressing Kv1.5.

From: Enhancement of 5-HT2A receptor function and blockade of Kv1.5 by MK801 and ketamine: implications for PCP derivative-induced disease models

Fig. 2

a Representative Kv1.5 current tracings elicited by voltage steps shown in the figure inset in the absence and presence of MK801 (100 and 300 µM). b Kv 1.5 current amplitudes at + 50 mV are plotted against time. The period of application of various concentrations of MK801 is indicated as solid bars. c CRCs of (+) and (−) MK801 enantiomer-induced Kv1.5 inhibition. N in parentheses indicates the number of cells examined. N.S. not significant

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