Fig. 3: In silico analysis of HAT and BRD-containing protein expression in NB.

mRNA expression levels from 39 different BRD-containing proteins and 16 histone acetyltransferases were analyzed in neuroblastoma samples from the E-GEOD-3960 (n = 101) dataset. Samples were sorted according to disease stage and MYCN status. Heatmap represents the differentially expressed genes (p < 0.05) between the groups of patients with poor prognosis (stage 4, MYCN amplification) versus the remainder of patients (i.e., stage 1, 3, and 4 MYCN non-amplified)