Table 2 Current epigenetic drugs clinical trials in Neuroblastoma
Name of the drug | Type of drug | Phase | Estate | Number |
|---|---|---|---|---|
Decitabine | DNMT pan-inhibitor | Phase I | Complete | NCT01241162 |
Phase I | Complete | NCT00075634 | ||
Genistein | DNMT pan-inhibitor | Phase II | Recruiting | NCT02624388 |
Vorinostat | HDACi class I and II inhibitor | Phase I | Complete | NCT00217412 |
Phase I | Complete | NCT01132911 | ||
Phase II | Ongoing but not recruiting | NCT02035137 | ||
Phase I | Recruiting | NCT02559778 | ||
Phase I | Complete | NCT01019850 | ||
Phase I | Complete | NCT01208454 | ||
VAP | HDACi class I and II inhibitor | Phase I | Ccomplete | NCT01204450 |
4-PB | HDACi pan-inhibitor | Phase I | Complete | NCT00001565 |
GSK525762 | iBET | Phase I | Recruiting | NCT01587703 |
