Fig. 4: Retinal architecture of ipo13-deficient morphants.
From: Mutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract
Left panel shows the control MO 5.0 ng, ipo13-MO 1.0 ng, and ipo13-MO 2.5 ng injected larvae expressing zpr-1 in relative normal levels at 3 dpf. Less zpr-1 signal is detected in the peripheral area of larval retinas. The three nuclear layers are even in these three groups. Right panel shows that ipo13-MO 5.0 ng injection disturbs the lamination of retinal nuclear layers. Both plexiform layers are not observed in this group, and almost no zpr-1 expression is detected
