Fig. 2: Gene network of DEGs between major depressive disorder patients and healthy controls. | Experimental & Molecular Medicine

Fig. 2: Gene network of DEGs between major depressive disorder patients and healthy controls.

From: Differentially expressed genes related to major depressive disorder and antidepressant response: genome-wide gene expression analysis

Fig. 2

Twelve genes related to signal transduction and the immune system are involved in this network with an uncorrected p-value < 0.05. APH1A, aph-1 homolog A, gamma secretase subunit; EGF, epidermal growth factor; EPHB4, EPH receptor B4; HLA-E, major histocompatibility complex class I E; IGKC, immunoglobulin kappa constant; LRRFIP1, leucine-rich repeat (in FLII) interacting protein 1; NCK1, NCK adaptor protein 1; PIK3R1, phosphoinositide-3-kinase regulatory subunit 1; SH2D2A, SH2 domain containing 2A; SOS1, SOS Ras/Rac guanine nucleotide exchange factor 1; STAM2, signal transducing adaptor molecule 2; YES1, YES proto-oncogene 1, Src family tyrosine kinase

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