Fig. 5: circRNA_104670 promotes the expression of MMP-2 and inhibits the expression of collagen II. | Experimental & Molecular Medicine

Fig. 5: circRNA_104670 promotes the expression of MMP-2 and inhibits the expression of collagen II.

From: CircularRNA_104670 plays a critical role in intervertebral disc degeneration by functioning as a ceRNA

Fig. 5

a, b Immunofluorescence staining for collagen II after transfection with si-circRNA_104670 or co-transfection with si-circRNA_104670 and si-miRNA-17-3p, scale bar, 40 μm. c, d Immunofluorescence staining for MMP-2 after transfection with si-circRNA_104670 or co-transfection with si-circRNA_104670 and si-miRNA-17-3p, scale bar, 40 μm. e–g Collagen II and MMP-2 protein expression levels were analyzed by Western blotting. GAPDH was used as a loading control. The presented values are the means ± SD. of three different preparations, *p < 0.05; **p < 0.01; ***p < 0.001

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