Fig. 1: ENPP1 deficiency leads to decreased levels of PPi and elevated levels of ATP in the plasma of GACI individuals and ttw/ttw mice. | Experimental & Molecular Medicine

Fig. 1: ENPP1 deficiency leads to decreased levels of PPi and elevated levels of ATP in the plasma of GACI individuals and ttw/ttw mice.

From: ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP

Fig. 1

Plasma levels of PPi (a, b) and ATP (c, d) were determined from healthy controls (n = 10) and GACI patients (n = 4) (a, c) and from 7-week-old WT (n = 6) and ttw/ttw mice (n = 5) (b, d). Plasma levels of ATP from healthy controls (c) correspond to normal human EDTA plasma concentrations from previous publications27. Values are presented as the mean ± SD. **p < 0.005, ***p < 0.001 (Student’s t test, unpaired two-sample testing for means)

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