Fig. 5: Regenerative effects of FGF-2 on the elastase-induced emphysema model.

The mice were intratracheally injected with 0.4 U of porcine elastase on day 0. Aliquots (10 pg) of FGF-2 and PD173074 were intranasally and intraperitoneally administered on days 7–13. The mice were killed on day 14. a MLI (n = 4–6 per group). P-values were determined by the Mann–Whitney test; *p < 0.05. b Lung histology with H&E staining (scale bar = 1 mm)