Fig. 1: Decreased expression of LOX and LOXL2 was found in preeclamptic placentas. | Experimental & Molecular Medicine

Fig. 1: Decreased expression of LOX and LOXL2 was found in preeclamptic placentas.

From: Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia

Fig. 1

a Representative images of expression and localization of LOX family members in first trimester villi by immunohistochemistry analysis. Brownish color represents positive staining of LOX family members. Arrows, trophoblasts; arrowheads, cytotrophoblasts. b Western blot analysis of LOX family members in placentas from normal full-term pregnancies and preeclampsia patients. c Statistical analysis of protein densitometry quantification of western blot analysis (b) by Student’s t-test. Data are presented as the means ± SEM. d mRNA expression of LOX family members was analyzed by quantitative reverse-transcription PCR. Statistical data were analyzed by Student’s t-test. Data are presented as the means ± SEM. *P < 0.05; **P < 0.01; and ****P < 0.0001

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