Fig. 2: Significantly altered bacterial taxa in UUO rats. | Experimental & Molecular Medicine

Fig. 2: Significantly altered bacterial taxa in UUO rats.

From: Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Fig. 2

a LDA score of the significantly discriminant genera between the two groups (LDA score > 2.0, Wilcoxon rank-sum tests, P < 0.05). b Boxplots showing differences in the relative abundance of nine significantly discriminant taxa driving gut microbiome differences between the UUO and sham rats. Boxplots labeled with different asterisks indicated taxa abundances are significantly different between the UUO and sham rats. Single and double asterisks indicated P < 0.05 and P < 0.01 obtained by using Wilcoxon rank-sum tests, respectively. c Heatmap of nine significantly discriminant taxa in the sham and UUO rats, where rows represent bacterial taxa indicated. Columns represent colonic luminal content samples collected from the UUO and sham rats. Asterisks denote statistical significance between the sham and UUO groups (n = 6), *P < 0.05, **P < 0.01. d Correlations of nine significantly discriminant taxa in the UUO and sham rats by using Spearman correlation analysis; Asterisks denote statistical significance between bacterial taxa, *P < 0.05, **P < 0.01

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