Fig. 7: The TBK1 inhibitor Amlexanox alleviated radiation-induced pulmonary injury and fibrosis. | Experimental & Molecular Medicine

Fig. 7: The TBK1 inhibitor Amlexanox alleviated radiation-induced pulmonary injury and fibrosis.

From: Blocking TBK1 alleviated radiation-induced pulmonary fibrosis and epithelial-mesenchymal transition through Akt-Erk inactivation

Fig. 7

The lung area of mice was exposed to local irradiation at a dose of 15 Gy, and HE (a) and Masson staining (c) were conducted at 1 to 12 months postirradiation. Lung fibrosis (b) and collagen (d) deposition were quantified in lung sections from different groups. At different time points, hydroxyproline content was measured via ELISA in different groups (e). *P < 0.05 and **P < 0.01

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