Fig. 3: Development of a novel PDX model of glioblastoma via intravitreal injection.
From: Development of a patient-derived xenograft model of glioblastoma via intravitreal injection in mice
a A schematic diagram demonstrating the intravitreal injection of tumor cells. b The relative proportion of mice with grade 2–5 disease after the intravitreal injection of GBL-28 and GBL-37 cells that underwent normal culture conditions. c The relative proportion of mice with grade 3 or 4 disease after the intravitreal injection of GBL-28 and GBL-37 cells that underwent hypoxia treatment for 4 h before injection. d Representative images of H&E-stained sections of the eyeball at 4 weeks after the intravitreal injection of GBL-28 or GBL-37 cells that underwent hypoxia treatment for 4 h before injection. The yellow dashed lines indicate the lens and retina. Scale bar: 1 mm
