Fig. 7 | Experimental & Molecular Medicine

Fig. 7

From: microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model

Fig. 7

miR-328 inhibition in M2 macrophages suppresses the progression of PF by targeting FAM13A. a Masson staining to examine the degree of PF in rats after the inhibition of miR-328 and FAM13A (400 × ). b IHC to analyze the expression of α-SMA and Collagen I in rats after the inhibition of miR-328 and FAM13A (400 × ). c MOD values of α-SMA and Collagen I in rats after the inhibition of miR-328 and FAM13A. miR-328, microRNA-328; PF, pulmonary fibrosis; FAM13A, family with sequence similarity 13, member A; α-SMA, α-smooth muscle actin; IHC, immunohistochemistry; and NC, negative control. * p < 0.05 vs. the control group; # p < 0.05 vs. the antagomir NC + sh-NC group. All results were measurement data and were analyzed using one-way analysis of variance. The results are expressed as the mean ± standard deviation; n = 6

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