Fig. 1: Acetate attenuates inflammasome activation in vitro. | Experimental & Molecular Medicine

Fig. 1: Acetate attenuates inflammasome activation in vitro.

From: Acetate attenuates inflammasome activation through GPR43-mediated Ca2+-dependent NLRP3 ubiquitination

Fig. 1

a–d ELISA of IL-1β (a, b) and IL-18 (c, d) in BMDMs treated with LPS + nigericin or LPS + ATP at different doses (20, 30, 35, 40, and 60 mM) (n = 3); e ELISA of IL-1β after sodium acetate treatment (n = 3); f ELISA of IL-1β at different time points after acetate treatment in LPS-primed ATP-treated BMDMs (n = 3); n = biological replicates; Data are presented as the mean ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001, Student’s t-test compared with the control group

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