Fig. 1: Higher resistance of TBX18-iPMs to metabolic stresses.
From: Induced cardiac pacemaker cells survive metabolic stress owing to their low metabolic demand
a TBX18- and GFP-NRVMs were incubated in normoxia or 1% oxygen (Hypoxia) with or without 2-DG treatment for 3 days from D3 to D6, followed by ethidium homodimer-1 (EthD-1) staining on D6. The % cell death was calculated based on the number of EthD-1+ cells per total cells. Representative pictures of EthD-1 and Hoechst 33342 staining of D6 GFP- and TBX18-NRVMs. b Quantitative graphs of % cell death (n ≥ 8 for each condition). Scale bar: 10 µm *p < 0.05
