Table 3 Tumorigenicity of Hep3B and Huh7 spheres

From: Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation, invasion, and self-renewal of hepatocellular carcinoma stem cells

Injected cells

Hep3B

Hep3B spheres

Huh7

Huh7 spheres

5 × 103

1/6

2/6

0/6

2/6

1 × 104

0/6

3/6

1/6

4/6

5 × 104

2/6

4/6

2/6

5/6

1 × 105

3/6

5/6

3/6

6/6

Total

6/24 (25.00%)

14/24 (58.33%)*

6/24 (25.00%)

17/24 (70.83%)#

  1. Note: *p < 0.05 vs. Hep3B cells; #p < 0.05 vs. Huh7 cells; the experiments were repeated six times
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