Fig. 1: USP21 is overexpressed in non-small-cell lung cancer (NSCLC) tissues and cells.

a Transcript levels of USP21 in lung cancer patients and normal tissues using the LUAD and LUSC data set of The Cancer Genome Atlas. b The relative USP21 expression levels of 42 paired lung cancer tissue samples compared to adjacent normal tissues. c Western blot analyses of the samples for USP21 with adjacent normal tissue samples as the controls. β-Actin was used as an internal control. d Immunohistochemical staining of tissue samples for USP21 with adjacent normal tissue samples as the controls. Scale bar = 50 μm. e The relative expression levels of USP21 in multiple NSCLC cell lines, A549, H1299, NCI-H520, and NCI-H460 and normal control 16HBE cells. The means ± SD (n = 3) are shown in b, e. *p < 0.05, **p < 0.01, ***p < 0.001 vs. the corresponding control.