Fig. 1: e-selectin, sICAM-1, and PTEN expression levels were increased in patients with diabetes and rats.

a Plasma e-selectin was measured in patients with diabetes and healthy volunteers (con: n = 30, DM: n = 50). b Plasma sICAM-1 was measured in patients with diabetes and healthy volunteers (con: n = 30, DM: n = 50). c The mRNA expression of e-selectin was examined by qPCR in peripheral blood mononuclear cells in the subjects (con: n = 30, DM: n = 50). d The mRNA expression of sICAM-1 was examined by qPCR in peripheral blood mononuclear cells in the subjects (con: n = 30, DM: n = 50). e Results from the western blot analysis of PTEN and p-p65 expressions in peripheral blood mononuclear cells in the subjects (con: n = 30, DM: n = 50). f The mRNA expression of PTEN was examined by qPCR in peripheral blood mononuclear cells in the subjects (con: n = 30, DM: n = 50). g Plasma e-selectin was measured in the control group and diabetic group rats (n = 5/group). h Plasma sICAM-1 was measured in the control group and diabetic group rats (n = 5/group). i The mRNA expression of e-selectin was examined by qPCR in rat aortic tissues in the control group and the diabetic group (n = 5/group). j The mRNA expression of ICAM-1 was examined by qPCR in rat aortic tissues from the control group and the diabetic group (n = 5/group). k Results from the western blot analysis of e-selectin, ICAM-1, PTEN, and p-p65 expression in rat aortic tissues from the control group and the diabetic group (n = 5/group). l The mRNA expression of PTEN was examined by qPCR in rat aortic tissues from the control group and the diabetic group (n = 5/group). m Immunostaining of PTEN in rat aortic tissues from the control group and the diabetic group (n = 5/group). Scale bar, 20 μm. PBM peripheral blood mononuclear cells. *P < 0.05, compared with the control group.