Fig. 4: SET8 interacted with FOXO1. | Experimental & Molecular Medicine

Fig. 4: SET8 interacted with FOXO1.

From: SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN

Fig. 4

a Several proteins that interact with SET8 are shown in Fig. 3a (https://string-db.org). b Interactions between SET8 and FOXO1 in HUVECs were verified by Co-IP. c Colocalization of SET8 and FOXO1 in HUVECs was determined by confocal microscopy. d Results of the western blot analysis of FOXO1 in HUVECs cultured under normal or high-glucose conditions. e Results from the qPCR analysis of FOXO1 in HUVECs cultured under normal or high-glucose conditions. *P < 0.05, compared with the control group, n = 5/group.

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