Fig. 3: Clinical characteristics of premature mice.
From: Preterm birth is associated with epigenetic programming of transgenerational hypertension in mice
Birth body weight of premature or control mice, compared to E18.5 fetuses, expressed in grams, as the means ± SEM (fetuses n = 6, preterm D0 n = 14, control D0 n = 17) (a). Body weight of 6-month (M6)-old former premature males and control mice, expressed in grams, as the means ± SEM (n = 8 in each group) (b). Positive correlation between systolic blood pressure and body weight in M6 mice, obtained by Spearman regression analysis (c). Systolic blood pressure normalized to body weight ratio in former premature and control M6 male mice (n = 6 in each group) (d). Kidney weight to total body weight ratio in former premature and control M6 male mice (n = 6 in each group) (e). Glomerular density per mm³ measured in renal sections of former preterm and control M6 male mice (n = 3 in the control PBS group, n = 5 in the control LPS group, n = 4 in the preterm group) (f). *P < 0.05, **P < 0.01, ***P < 0.001 (compared to the control group); #P < 0.05, ##P < 0.01, ###P < 0.005 (compared to the fetus group). Nonparametric Mann–Whitney U-tests or Kruskal–Wallis test for comparison between 2 or 3 parameters, respectively.
