Fig. 1: Increased serum OPN levels with age in individuals with asthma.
From: Osteopontin contributes to late-onset asthma phenotypes in adult asthma patients
Comparison between a patients with asthma vs. HCs and b patients with LOA vs. those with EOA. P values were analyzed by the Mann–Whitney U test. **P < 0.01, ***P < 0.001 between the groups. Data are shown as log-transformed, mean ± SEM. c Correlation between serum OPN and age, analyzed by Spearman’s rank correlation coefficient. Diagnostic values of serum OPN level in the discrimination of individuals with asthma d and individuals with LOA e from HCs. AUC area under the curve; EOA early-onset asthma, HCs healthy controls, LOA late-onset asthma, OPN osteopontin, ROC receiver operating characteristic.
