Fig. 5: PROM2 activates the Akt signaling pathway. | Experimental & Molecular Medicine

Fig. 5: PROM2 activates the Akt signaling pathway.

From: PROM2 promotes gemcitabine chemoresistance via activating the Akt signaling pathway in pancreatic cancer

Fig. 5

a GSEA analysis showing the positive correlation between PROM2 expression and gene sets relevant to the Akt signaling pathway. b Immunoblotting assays demonstrating the expression level of the indicated proteins in AsPC-1 cells with different expression level of PROM2. c Luminescence signaling (left) and tumor weight (right) of the tumors formed by AsPC-1/PROM2 after treatment with vehicle or the Akt inhibitor (MK-2206) (*P < 0.05). d Representative images (left) and quantification (right) of TUNEL and active caspase-3 in tumors with the indicated treatment (*P < 0.05).

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