Table 1 Top 3 functional clusters enriched from the upregulated (fold change >1.5) phosphoproteins in HuH-7R cells.

From: Quantitative phosphoproteomic analysis identifies the potential therapeutic target EphA2 for overcoming sorafenib resistance in hepatocellular carcinoma cells

  

Count

p Value

Annotation cluster 1

Enrichment Score: 29.78

  

GOTERM_MF_DIRECT

Cadherin binding involved in cell-cell adhesion

60

3.80E−33

GOTERM_CC_DIRECT

Cell–cell adherens junction

62

3.90E−33

GOTERM_BP_DIRECT

Cell–cell adhesion

50

3.10E−25

Annotation cluster 2

Enrichment Score: 7.24

  

GOTERM_MF_DIRECT

Protein serine/threonine kinase activity

36

1.40E−09

GOTERM_BP_DIRECT

Protein phosphorylation

37

5.90E−08

GOTERM_MF_DIRECT

Protein kinase activity

29

2.30E−06

Annotation cluster 3

Enrichment Score: 4.21

  

GOTERM_MF_DIRECT

Structural constituent of cytoskeleton

18

1.80E−08

GOTERM_BP_DIRECT

Microtubule-based process

9

7.10E−06

GOTERM_MF_DIRECT

GTPase activity

16

3.60E−03

GOTERM_MF_DIRECT

GTP binding

19

3.20E−02

  1. MF molecular function, CC cellular function, BP biological process.