Fig. 7: l-CDL-induced suppression of phosphorylated PKC γ, MAPK, CREB, and CaMKII was abolished by intrathecal administration of D1DR, D2DR, and D1–D2DR agonists. | Experimental & Molecular Medicine

Fig. 7: l-CDL-induced suppression of phosphorylated PKC γ, MAPK, CREB, and CaMKII was abolished by intrathecal administration of D1DR, D2DR, and D1–D2DR agonists.

From: The dopamine D1–D2DR complex in the rat spinal cord promotes neuropathic pain by increasing neuronal excitability after chronic constriction injury

Fig. 7

a, b Western blotting showing the phosphorylation levels of PKC γ, CaMKII, CREB, JNK, p38, and ERK in the spinal cord after coadministration of l-CDL (15 μg/20 μL) with SKF 38393, quinpirole, and SKF 83959 (n = 4; #P < 0.5, ##P < 0.01 vs the control group; *P < 0.05, **P < 0.01 vs the CCI group; $P < 0.05, $$P < 0.01 vs the l-CDL group).

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