Fig. 2: HFD-fed Ahnak-deficient mice have attenuated lipid clearance but not VLDL secretion.

a Lipid clearance was estimated by measuring blood TG levels after oral olive oil administration. b Analysis of gene expression involved in VLDL secretion and lipid uptake after a 7-week HFD feeding by quantitative real-time PCR normalized to 36B4 (n = 4–6 mice). c VLDL secretion. Mice were treated with Poloxamer 407 to block VLDL clearance, and VLDL secretion was then estimated by measuring blood TG levels after Poloxamer 407 treatment. Data were presented as the means ± SEM. *p < 0.05; **p < 0.01.