Fig. 1: Phylogenetic background and genomic structure of SARS-CoV-2.

a Schematic depiction of the four genera of coronaviruses, their evolutionary relationship, and their animal hosts. The phylogenetic relationships established by Woo et al.4 were used to draw the figure. b Genomic distribution of all open reading frames (ORFs) across the 29,903 bp SARS-CoV-2 genome. The nucleocapsid (N), spike (S), membrane (M), and envelope (E) proteins are color-coded according to the image of the virus. All other ORFs correspond to nonstructural proteins. The yellow panel shows an enhanced view of an 8,340 bp region encompassing 9 ORFs and the three-prime untranslated region (3′-UTR).