Fig. 6: PPARγ levels are decreased in the airway epithelial cells of COPD patients.

a, b Large airway epithelial cells were obtained from never-smokers (n = 4), smokers (n = 4) and COPD patients (n = 4). c, d Small airway epithelial cells were acquired from never-smokers (n = 4), smokers (n = 8) and COPD patients (n = 11). Total cell lysates were subjected to western blot analysis for PPARγ and GAPDH quantification (a, c). The gel data were quantified using Scion image densitometry (b, d). The data represent mean ± SE; **P < 0.05. Abbreviations: PPARγ, peroxisome proliferator-activated receptor gamma; COPD, chronic obstructive pulmonary disease; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; SE, standard error.