Fig. 4: Personalized medicine based on the testing of individual PDOs.
From: Gastrointestinal cancer organoids—applications in basic and translational cancer research
Different co-clinical studies have revealed the feasibility and potential use of PDOs as a predictive tool for therapy response testing. To this end, generated PDOs from cancer patients were treated in vitro with chemotherapy, irradiation or targeted therapy, and the obtained response data were correlated to the clinical responses of patients.
