Table 1 List of identified proteins in rat heart by peptide mass fingerprinting (PMF) analysis.

From: MicroRNA-26a/b-5p promotes myocardial infarction-induced cell death by downregulating cytochrome c oxidase 5a

Spot ID

Description

Gene name

Acc. no.a

Monoisotopic mass (Mr)

Calculated PI

Scoreb

Fold changes (MI/CON)

p valuec

1

Peroxiredoxin-2

Prdx2

NP_058865.1

21,941

4.41

62

0.50

0.000

5

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8

Ndufs8

NP_001099792.1

24,411

5.87

66

0.31

0.001

6

ATP synthase subunit d

Atp5pd

NP_062256.1

18,809

5.45

100

0.03

0.009

9

Cytochrome c oxidase subunit 5a precursor

Cox5a

NP_665726.1

16,347

6.08

66

0.47

0.009

10

Heat shock protein β-6

Hspb6

NP_620242.1

17,551

6.05

155

0.09

0.018

13

NADH dehydrogenase [ubiquinone] flavoprotein 2 precursor

Mdufv2

NP_112326.1

27,703

6.23

113

0.61

0.012

14

Adenine phosphoribosyltransferase

Aprt

NP_001013079.1

19,761

6.17

145

0.39

0.014

15

V-set and transmembrane domain-containing protein 2A

Vstm2a

XP_008765103.1

24,560

6.21

88

0.40

0.010

16

Annexin A5

Anxa5

NP_037264.1

35,779

4.99

296

0.41

0.018

19

Mitochondrial aldehyde dehydrogenase precursor

Aldh

AAS75814.1

56,079

6.69

230

1.38

0.038

20

Fatty acid-binding protein

Fabp3

NP_077076.1

14,766

5.9

124

0.72

0.049

24

α-enolas

Eno1

XP_006239506.1

47,627

5.9

169

1.27

0.014

25

Dihydrolipoamide S-acetyltransferase

Dlat

pir| |I55976

48,117

5.97

116

0.68

0.003

29

NADH dehydrogenase (ubiquinone) 1α subcomplex 10 precursor

Ndufa10

NP_955789.2

40,753

7.64

183

0.18

0.082

30

Cytochrome c oxidase subunit 5a precursor

Cox5a

NP_665726.1

16,347

6.08

157

0.80

0.043

32

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3

Ndufs3

NP_001099959.1

30,379

7.07

182

0.16

0.081

33

NADH dehydrogenase (ubiquinone) Fe-S protein 1

Ndufs1

EDL98902.1

74,362

5.74

204

0.40

0.011

34

Vinculin

Vcl

EDL86257.1

124,126

5.54

107

0.29

0.027

35

Pyruvate dehydrogenase E1 component subunit β precursor

Pdhb

NP_001007621.1

39,299

6.2

71

0.39

0.057

41

Hypoxanthine-guanine phosporibosyltransferase

LOC103689983

AAA41351.1

18,043

8.9

110

0.41

0.084

43

3-mercaptopyruvate sulfurtransferase

Mpst

NP_620198.1

33,205

5.88

123

0.38

0.033

43

Annexin A3

Anxa3

EDL99639.1

36,744

5.72

64

0.38

0.033

44

Myosin light chain 3

Myl3

NP_036738.1

22,256

5.03

121

0.65

0.020

  1. CON control rat group, MI rat group with myocardial infarction.
  2. aAcc. no. is the NCBIprot database accession number.
  3. bProtein score equals −10*Log (P), where P is the probability that the observed match is a random event. Protein scores greater than 62 are significant (p < 0.05).
  4. cSignificant differences between CON and MI groups were determined via ANOVA.
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