Fig. 7: MHY-1685-primed hCSCs improve vascular regeneration through angiogenesis and differentiate into ECs. | Experimental & Molecular Medicine

Fig. 7: MHY-1685-primed hCSCs improve vascular regeneration through angiogenesis and differentiate into ECs.

From: Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair

Fig. 7

a Representative images of the capillary density in the infarct zone, border zone, and remote zone 4 weeks after MI and their quantification summary. CD31 (green), DAPI (blue). n = 4–5. (*p < 0.05 vs. control, #p < 0.05 vs. senescent hCSC). Scale bar: 100 µm. b Representative images of hCSCs differentiated into ECs and proliferation in the infarct zone and quantification summary. IL-B4 (green), DiI-labeled hCSCs (red), Ki-67 (white), DAPI (blue). n = 3. (*p < 0.05 vs. senescent hCSC). Scale bar: 30 µm. Data are shown as the mean ± S.E.M.

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