Fig. 2: Three strategies for detecting genome-wide mutations in single cells.
From: Dissecting single-cell genomes through the clonal organoid technique
Three different strategies that can be applicable for detecting single-cell mutations are illustrated with brief experimental steps. Expected outcomes from each of the strategies are shown below with summaries of source genomes and sequence reads produced from the source. True, borderline, and false findings are highlighted with green, orange, and red boxes, respectively. LCM laser-capture microdissection.
