Fig. 4: Inflammation response were reduced by NLRC4 siRNA after ICH. | Experimental & Molecular Medicine

Fig. 4: Inflammation response were reduced by NLRC4 siRNA after ICH.

From: The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats

Fig. 4

a–g, j Western blot assay to detect NLRC4, pNLRC4, Pro-IL-1β, IL-1β, Pro-caspase-1, caspase-1, Pro-IL-18, IL-18, TNF-α, and IL-6, (k, l) ELISA for IL–18 and IL–1β (h, i) Immunostaining for MPO-positive cells (×400 and ×200) at peri-hematoma area in sham, ICH, negative control siRNA, and NLRC4 siRNA groups at 72 h after ICH (six rats for each group). *P < 0.05, compared with ICH.

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