Fig. 5: RGS2 affected NLRC4 inflammasome activation following ICH.

a–f Western blot assay was used to detect the expression of RGS2, pNLRC4, NLRC4, Pro-caspase-1, caspase-1, Pro-IL-1β, IL-1β, Pro-IL-18, and IL-18, in perihematomal area in ICH, Sham, ICH + shRGS2, ICH + negative control shRNA (ICH + NC shRNA), ICH + shRGS2 + si-NLRC4 and ICH + shRGS2 + NC siRNA at 72 h after ICH (6 rats for each group).