Fig. 6: PM exposure stimulates SERPINB2 expression in endometrial stem cells in vitro. | Experimental & Molecular Medicine

Fig. 6: PM exposure stimulates SERPINB2 expression in endometrial stem cells in vitro.

From: The impact of fine particulate matter (PM) on various beneficial functions of human endometrial stem cells through its key regulator SERPINB2

Fig. 6

We hypothesized that SERPINB2 could act as a key mediator of PM-induced toxic effects in endometrial stem cells. Endometrial stem cells (a), fibroblasts (b), and vascular endothelial cells (c) were treated with or without PM (25 μg/ml) for 72 h. Real-time PCR and western blotting were performed to confirm the increase in SERPINB2 expression by PM exposure in vitro. The GEO database was also analyzed to further verify the correlations between the increased SERPINB2 level and exposure to air pollutants (d). β-Actin was used as the internal control. The bar graphs show the average of three independent experiments. Significant differences are presented. *p < 0.05, **p < 0.005, and ***p < 0.001 (two-sample t-test).

Back to article page