Table 1 Demographic data of the participants (n = 221).

From: Application of QPLEXTM biomarkers in cognitively normal individuals across a broad age range and diverse regions with cerebral amyloid deposition

Characteristics (n)

CN− (185)

CN+ (36)

P value

Sex, M/F

80/105

20/16

0.1755b

Age, years, mean ± SEM

55.89 ± 1.2

74.47 ± 1.0

<0.0001a

Education, mean ± SEM

12.82 ± 0.3

12.08 ± 0.8

0.3846

MMSE raw score, mean ± SEM

27.78 ± 0.2

27.17 ± 0.4

0.1346

MMSE z score, mean ± SEM

0.48 ± 0.1

0.44 ± 0.1

0.7873

CDR (n)

0 (185)

0 (36)

–

ApoE4 positivity, ε4 + /N (%)

40/185 (22%)

12/36 (33%)

0.1305b

PiB (SUVR), mean ± SEM

1.09 ± 0.004

1.62 ± 0.05

<0.0001a

  1. CN Cognitively normal, PiB Pittsburgh compound B, − or + PiB positivity, SEM standard error of the mean, n number of participants, MMSE Mini-Mental State Examination, MMSE z score revised value of the MMSE score with consideration for age, sex, and education level, CDR Clinical Dementia Rating, ApoE Apolipoprotein E, SUVR Standardized uptake value ratio, N total number of participants.
  2. asignificance by t test.
  3. bsignificance by chi-square test.
Back to article page