Fig. 1: Promoting the expression of HSP70 attenuated compression-induced NP cell death. | Experimental & Molecular Medicine

Fig. 1: Promoting the expression of HSP70 attenuated compression-induced NP cell death.

From: HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3

Fig. 1

a The effects of different concentrations of TRC on the expression of HSP70 in NP cells (N = 3). b The effects of TRC on the viability of NP cells exposed to 0, 24, and 48 h of compression (N ≥ 3). c The effects of TRC on the expression of HSP70 in NP cells under compression (N = 3). d Representative fluorescence photomicrograph of live and dead cell staining of NP cells (N = 3, scale bar: 100 μm). e The effects of VER on the viability of NP cells treated with TRC (N ≥ 3). f The effects of HSP70 siRNA on the viability of NP cells treated with TRC (N ≥ 3). (*P < 0.05; **P < 0.01; ***P < 0.001 vs. the TRC 0 μM group or the TRC+, VER 0 μM group, ###P < 0.001 vs. the TRC−, VER 0 μM group or the TRC−, siNC+, siHSP70− group, NS not significant).

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