Fig. 3: Promoting the expression of HSP70 attenuated IVDD in vivo.

a HE and safranin-O/fast green staining of IVD samples. b Evaluation of IVDD by histological score. c, d IHC staining of matrix metalloproteinase 13 (MMP13) and quantitative analysis. e, f IHC staining of cleaved caspase 3 and quantitative analysis. (n = 7/group, *P < 0.05; **P < 0.01; ***P < 0.001).