Fig. 4: Immunoregulatory potential of the CMKLR1+ MSC functional subpopulation. | Experimental & Molecular Medicine

Fig. 4: Immunoregulatory potential of the CMKLR1+ MSC functional subpopulation.

From: Single-cell RNA sequencing analysis of human bone-marrow-derived mesenchymal stem cells and functional subpopulation identification

Fig. 4

a The proliferative ability of CMKLR1+ MSCs was weaker than that of CMKLR1− MSCs. b PCR results showed that CCL2, TGF-β, IGFBP2, PTX3, GREM1, and CTGF expression levels were higher in CMKLR1+ MSCs than in CMKLR1− MSCs. c The immunoregulatory ability of CMKLR1+ MSCs determined by CFSE-based flow cytometry assays was stronger than that of CMKLR1− MSCs. d The immunoregulatory ability of MSCs determined by CFSE-based flow cytometry assays was positively related to the percentage of CMKLR1+ MSCs.

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