Fig. 1: RTN3-null mice presenting phenotypes of CKD and kidney fibrosis. | Experimental & Molecular Medicine

Fig. 1: RTN3-null mice presenting phenotypes of CKD and kidney fibrosis.

From: Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells

Fig. 1

a HE, b picrosirius red, and c PAS staining analysis showing the glomeruli in WT (n = 5) and RTN3-null mice (n = 5) of different ages. d Statistical evaluation of glomerulosclerosis in WT and RTN3-null mice of different ages. e, f Masson staining illustrating the distribution of collagen in the kidney tissues of WT (n = 5) and RTN3-null mice (n = 5) of different ages.

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