Fig. 2: RTN3 levels are decreased in CKD patients. | Experimental & Molecular Medicine

Fig. 2: RTN3 levels are decreased in CKD patients.

From: Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells

Fig. 2

a, b Western blot analysis showing the expression levels of RTN3 in normal individuals (n = 2) and CKD patients (n = 4). c IHC analysis showing RTN3 expression levels in kidney tissues from healthy control subjects (n = 4) or CKD patients (n = 24). The red dots represent samples with lower RTN3 levels. d PAS, Masson, and IHC staining showing the conditions of glomerulosclerosis, kidney fibrosis, and RTN3 expression among patients with CKD of different stages. e Statistical analysis of Masson staining and IHC in the healthy group, slight-glomerulosclerosis group, and severe-glomerulosclerosis group.

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