Fig. 4: TAS1 performs its biological functions by cis-activating TMPO transcription. | Experimental & Molecular Medicine

Fig. 4: TAS1 performs its biological functions by cis-activating TMPO transcription.

From: LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription

Fig. 4

a The correlation between TAS1 and TMPO mRNA expression in clinical ESCC tissues (SYSUCC, n = 97, Pearson correlation analysis). b Detection of TMPO expression by qPCR and WB in KYSE150 and TE-11 cells with TAS1 KD compared with control cells (n = 3). c Detection of TAS1 expression by qPCR in KYSE150 and TE-11 cells with TMPO KD compared with control cells (n = 3). d MTS assays were performed to evaluate the proliferation (OD 490 nm) of KYSE150 and TE-11 cells with TMPO KD (n = 3). e Statistical analysis of the migration and invasion rates (%) of KYSE150 and TE-11 cells with TMPO KD (n = 3). f–h MTS assays and statistical analysis of the cell cycle distribution (%) of KYSE150 cells treated as indicated and the migration and invasion rates (n = 3). i A schematic diagram of the NRO assay. The data are presented as the mean±S.D. values. *P < 0.05; **P < 0.01; ***P < 0.001; ns, not significant.

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